Barttner syndrome is a disorder where the kidneys dispose of electrolytes (potassium, sodium and chloride) in excessive amounts, so that the levels of potassium in the blood becomes low (hypokalemia) and hormone levels of aldosterone and high renin.

CAUSE
Barttner syndrome is usually a hereditary disease and is caused by recessive genes. Patients get two of these genes from both parents.

SYMPTOMS
Children are growing slowly and appear malnourished. Muscle weakness, feeling of excessive thirst, removing large amounts of urine and mentally retarded.

Sodium chloride and water levels in the blood becomes low.
Body tries to compensate by producing more aldosterone and renin. These hormones cause decreased levels of potassium in the blood.

Diagnosis
Diagnosis based on symptoms and results of laboratory tests that show abnormalities in the levels of potassium and hormones in the blood.

TREATMENT
Symptoms can be prevented by taking potassium per-oral (swallowed) and drugs that reduce the disposal of potassium into the urine, such as spironolactone (aldosterone also inhibits the work), triamteren, amiloride, propranolol or indometacin. To compensate for the loss of excess fluid, the patient should drink plenty of water.

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